Breast cancer medscape
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After registering for free, Medscape automatically delivers specialty content to you that best fits your profile. Metastatic Breast Cancer Herceptin is indicated: In combination with paclitaxel for the first line treatment of HER2-overexpressing metastatic breast cancer As a single agent for treatment of HER2-overexpressing breast cancer in patients who have received one or more chemotherapy regimens for metastatic disease Select patients for therapy based on an FDA-approved companion diagnostic for Herceptin Metastatic Gastric Cancer Herceptin is indicated, in combination with cisplatin and capecitabine or 5-fluorouracil, for the treatment of patients with HER2 overexpressing metastatic gastric or gastroesophageal junction adenocarcinoma, who have not received prior treatment for metastatic disease. The incidence and severity was highest in patients receiving Herceptin with anthracycline-containing chemotherapy regimens Evaluate left ventricular function in all patients prior to and during treatment with Herceptin. Discontinue Herceptin treatment in patients receiving adjuvant therapy and withhold Herceptin in patients with metastatic disease for clinically significant decrease in left ventricular function Infusion Reactions; Pulmonary Toxicity Herceptin administration can result in serious and fatal infusion reactions and pulmonary toxicity. Symptoms usually occur during or within 24 hours of Herceptin administration.
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A biopsy may be done to get a definite diagnosis. Different types of biopsies include: Excisional removal of the lump by a surgeon Stereotactic needle biopsy using a machine like a mammogram Ultrasound-guided needle biopsy using ultrasound Women in their teens or early 20s may not need a biopsy if the lump goes away on its own or if the lump does not change over a long period. Treatment If a needle biopsy shows that the lump is a fibroadenoma, the lump may be left in place or removed.